AD performed significantly better than FA ( p = 0.02) or RD ( p < 0.0001). For the classification problem T2L vs NAWM, on average RD performed significantly better than AD ( p < 0.0001) or FA ( p = 0.02). The patient‐averaged ROC curve (average true positive rate depending on the fixed false positive rate) is plotted for each metric. For each patient, a ROC curve was computed for each classification problem: T2L vs NAWM (left plot), T1L vs NAWM (middle plot) and T1L vs T2L (right plot). Acronyms: NAWM = normal appearing white matter, T2L = T2‐hyperintense only lesional tissue, T1L = T2‐hyperintense lesional tissue that appears also T1‐hypointense.įig. In T1L CSF volume fraction was significantly higher than in T2L ( t = −13.3, p < 0.0001). In NAWM CSF volume fraction was significantly different from 0 ( t = 4.5, p < 0.0001), while it was significantly higher in T2L than in NAWM ( t = 18.1, p < 0.0001). A boxplot across the included 105 patients is shown for global normalised (median z‐score) CSF volume fraction within each tissue‐state for each patient.
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